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Monday, November 26, 2012

Osteoarthritis:

A degenerative disease of joints resulting from wear of the articular cartilage , which may lead to secondary changes in the underlying bone.

Etiology:

Primary: Unknown

Secondary:

·         Trauma
·         Occupational overuse of a joint
·         Metabolic diseases:
·         Hyperparathyroidism
·         Ochronosis alcaptonuria
·         Neurological disease:

·         Tabes dorsalis
·         Obesity

Pathophysiology:

·         Degeneration of cartilage
·         Hypertrophy of the bone
·         Thickening of synovial membrane
·         Reduction of the joint cavity (not obliterated)

Clinical features:

·         Onset : Insidious (slow)
·         Morning stiffness not more than 15 min
·         Pain:
Worse on activity
Relieved by rest
·         Asymmetrical joint involvement
·         Limited range of movement
·         Distal interphalangeal joint involvement as compared to rheumatoid arthritis
·         Number of joint involve is less as compared to rheumatoid arthritis

Investigations:

·         ESR will be normal because of no inflammation
·         X – ray:
·         Narrowing of joint space due to loss of cartilage
·         Formation of osteophytes at the margin of the joints
·         Cyst formation

Management:

General measures

·         Weight reduction
·         Rest
·         Joint protection

Physical therapy:

·         Heat therapy
·         Hydrotherapy
·         Proper exercises

Drug treatment:

·         Acetaminophen (Ponston)
·         NSAIDs
·         Inj. Triamcinolone

Surgery:

Joint replacement

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