There are four species of plasmodium (malarial parasite).
· Plasmodium Vivax
· Plasmodium Malariae
· Plasmodium Ovale
· Plasmodium Falciparum
Definitive host:
Female anopheles mosquito
Intermediate host:
Human
Life cycle in Human:
Sporozoites
=> merozoites (in liver) => merozoites (in RBCs) => release of
merozoites due to the RBC rupture, merozoites infect other RBCs. Some
merozoites differentiate into gametocytes => gametocytes containing
red cells are sucked by female anopheles mosquito.
Clinical features:
· High Grade Fever
· Rigor and Chill
· Sweating
The episode may come after 4, 6, 12, 24, 48 or 72 hrs.
Ø Cerebral Malaria can be caused by Plasmodium Falciparum.
Ø Black water syndrome is caused by Plasmodium Falciparum in which the patient has black urine due to hemolysis.
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